At Miracle Inside Diagnostic Scan Clinic in Leeds, we offer access to OncoNext® Risk genetic testing, a blood-based hereditary cancer risk test designed to identify inherited gene changes that may increase a person’s lifetime risk of developing certain cancers.
Hereditary Cancer Risk Genetic Testing
This test looks for germline mutations — inherited genetic changes present in all cells of the body, which may be passed down through families.
OncoNext® Risk is suitable for people who want to understand better their inherited cancer risk, especially where there is a family history of early-onset cancer, multiple cancers in the same family, or known hereditary cancer syndromes.
OncoNext® Risk Genetic Cancer Testing – Leeds
1 in 2 People Will Develop Cancer in Their Lifetime
Half of the UK population born after 1960 will be diagnosed with cancer during their lifetime. Alarmingly, nearly 50% are diagnosed after the cancer has already spread. Understanding your genome allows you to make proactive lifestyle and environmental changes to reduce your risk of developing cancers you may be genetically predisposed to.
At a Glance
- 1 Blood Sample
- 80 Gene Mutations Screened
- 10 Types of Cancer Screened
- Pre- and Post-Test Consultation Included
Why Choose OncoNext®?
Genes play a critical role in disease occurrence, and understanding your genome takes proactive healthcare to the next level. Most people carry inherited genetic mutations that increase their risk for certain cancers and diseases. While we cannot change our DNA, we can change our environment and lifestyle.
By knowing your genetic predisposition, OncoNext® empowers you to make informed decisions to reduce your cancer risk, through targeted lifestyle modifications and preventive care.
How Does OncoNext® Work?
Hereditary cancers often involve germline mutations – inherited changes in a gene that may increase cancer risk.
- Carrying a germline mutation does not guarantee cancer, but it lowers the threshold for environmental and lifestyle factors to trigger mutations in these genes.
- OncoNext® identifies these germline mutations, enabling you to modify lifestyle and environmental risks such as nutrition, smoking, sunlight exposure, and certain medications.
With OncoNext®, you can take control of your health, making proactive choices to reduce the likelihood of developing genetically predisposed cancers.
✅ Key Benefits
- Early identification of hereditary cancer risks
- Personalised actionable insights for prevention
- Comprehensive coverage for BRCA, breast, ovarian, bowel, prostate, and full cancer gene panels
- Expert consultation before and after testing
What Is OncoNext® Risk?
OncoNext® Risk is a genetic test that analyses selected cancer-related genes using advanced molecular testing.
The test focuses on genes involved in:
- DNA repair
- Tumour suppression
- Cell growth control
- Apoptosis regulation
Changes in these genes may increase susceptibility to specific types of cancer.
This is not a test to diagnose active cancer. It is designed to assess whether you carry inherited genetic variants that may increase your future risk.
Cancer Risk Panels Available
OncoNext® Risk testing is available for targeted cancer areas, including:
- Breast cancer
- Ovarian/uterine cancer
- Colon cancer
- Gastric cancer
- Pancreatic cancer
- Melanoma
- Prostate cancer
- Cerebral tumours
- Renal cancer
- Phaeochromocytoma/paraganglioma
- Complete hereditary cancer screening panel
Individual OncoNext® Risk Panels
Breast Cancer Risk Panel -£775
Includes genes such as:
ATM, BARD1, BRCA1, BRCA2, BRIP1, CDH1, CHEK2, PALB2, RAD51C, RAD51D, STK11, TP53, PTEN
Colon Cancer Risk Panel-£775
Includes genes such as:
APC, BMPR1A, CDH1, EPCAM, GREM1, MLH1, MSH2, MSH6, MUTYH, PMS2, POLD1, PTEN, SMAD4, STK11, TP53
Ovarian / Uterine Cancer Risk Panel -£775
Includes genes such as:
BRCA1, BRCA2, BRIP1, EPCAM, MLH1, MSH2, MSH6, PALB2, PMS2, PTEN, RAD51C, RAD51D, STK11, CHEK2, ATM
Pancreatic Cancer Risk Panel -£775
Includes genes such as:
ATM, BRCA1, BRCA2, CDKN2A, EPCAM, MLH1, MSH2, MSH6, PALB2, PMS2, STK11, TP53
Prostate Cancer Risk Panel -£775
Includes genes such as:
ATM, BRCA1, BRCA2, CHEK2, HOXB13, MLH1, MSH2, MSH6, NBN, PALB2, PMS2, TP53
BRCA1 / BRCA2 Genetic Test -£775
A focused test for inherited mutations in:
BRCA1 and BRCA2
These genes are strongly associated with hereditary breast and ovarian cancer risk.
OncoNext® Risk Complete Panel – £1175
The complete OncoNext® Risk panel screens approximately 80–82 genes associated with hereditary cancer predisposition.
- The full panel may include genes linked to breast, ovarian, bowel, gastric, pancreatic, prostate, melanoma, renal, thyroid and other hereditary cancer risks.
Take Control of Your Health: Understand Your Risks and Reduce Them. OncoNext analyses your genetic makeup to identify gene mutations that may increase your cancer risk. Many of these mutations are inherited and can be influenced by environmental factors and lifestyle choices. By understanding your genome, you can make informed adjustments to lower your cancer risk and take charge of your health for a healthier future..
Genes Screened
Onconext completely analyses your risk of developing the following cancers:
Breast
ATM, BARD, BRCA1, BRCA2, BRIP1 CDH1, CHEK2, MRETIA, MUTYH, NBN, NF, PALB2, PTEN, RADSO, RADSIC, RADSID, STK11, TP53
Ovarian / Uterine
BRCA1, BRCA2, BRIP1, EPCAM, MLH1,MSH2, MSH6, PALB2, PMS2, PTEN, RADS1C, RADS1D, STK11, TP53
Colon
APC, BMPR1A, CDH1, CHEK2, EPCAM, GREM1, MLH1, MSH2, MSH6, MUTYH, PMS2, POLD1, PTEN, SMAD4, STK11, TP53
Gastric
APC, BMPR1A, CDH1, EPCAM, MLHT, MSH2, MSH6, PMS2, STKT1, SMAD4, TPS3
Pancreas
APC, ATM, BMPR1A, BRCA1, BRCA2, CDKN2A, ERPCAM, MLH1, MSH2, MSH6, PALB2, PMS2, STKI1, TP53
Melanoma
BAP1, BRCA2, CDK4, CDKN2A, MITF, PTEN, RB1, TP53
Prostate
ATM, BRCA1, BRCA2, CHEK2, EPCAM, HOXB13, MLH1, MSH2, MSH6, NBN, PALB2, PMS2, RAD51D, TPS3
Cerebral
AIP, ALK, APC, CDKN1B, CDKN2A, DICER1, MEN1, MLH1, MSH2, MSH6, NBN, NF1, NF2, PHOX2B, PMS2, PRKARIA, PTCH1, PTEN, SMARCA4, SMARCBIT, SMARCE1, SUFU, TP53, TSCI, TSC2, VHL
Renal
BAP1, EPCAM, FH, FLCN, MET, MITF, MLH1, MSH2, MSH6, PMS2, PTEN, SDHA, SDHB, SDHC, SDHD, TP53,TSC1,TSC2,VHL
Pheochromocytoma / Paraganglioma
FH, MAX, MEN1, NF1, RET, SDHA, SDHAF2, SDHB, SDHC, SDHD, TMEMI27, VHL
Who Should Consider This Test?
This test may be suitable if you:
- Have a family history of cancer at a young age
- Have multiple relatives affected by cancer
- Have more than one cancer type in the family
- Have a known genetic mutation in the family
- Want to understand your inherited cancer risk
- Have been advised to consider genetic testing by a healthcare professional
Sample, Turnaround Time and Price
- Sample type: 10 mL EDTA blood sample
- Turnaround time: Approximately 15–30 working days from lab receipt, depending on panel
- Targeted panel price: From approximately £600
- Complete panel price: From approximately £700–£995
- Prices exclude shipping and handling where applicable
What Does a Positive Result Mean?
A positive result means a hereditary gene mutation has been detected.
This does not mean you currently have cancer, and it does not mean you will definitely develop cancer.
It may mean you have a higher inherited risk compared with the general population. This can help guide:
- Earlier screening
- More frequent surveillance
- Lifestyle risk reduction
- Referral to a genetic specialist
- Family cascade testing
- Preventive healthcare discussions
What Does a Negative Result Mean?
A negative result means no reportable mutation was found in the genes tested.
However, this does not completely remove cancer risk. Cancer can still occur due to non-inherited factors, lifestyle, environment, ageing or gene changes not covered by the test.
Why Choose Miracle Inside Diagnostic Scan Clinic?
At Miracle Inside in Leeds, we provide a professional and supportive pathway for private genetic testing.
We can help with:
- Test selection
- Sample collection guidance
- Private phlebotomy options
- Clear patient information
- Result pathway support
- Referral guidance where required
Book OncoNext® Risk Genetic Testing in Leeds
To discuss hereditary cancer risk testing or to book an appointment, contact Miracle Inside Diagnostic Scan Clinic.
Call: 01134408760
Website: www.miracleinside.com
Location: Leeds, West Yorkshire
FAQs
Is OncoNext® Risk a cancer diagnosis test?
No. OncoNext® Risk is not designed to diagnose active cancer. It checks for inherited genetic mutations that may increase lifetime cancer risk.
Is this test done from blood?
Yes. The test requires a blood sample, usually collected in an EDTA tube.
How much blood is needed?
Approximately 10 mL of blood is usually required.
How long do results take?
Results usually take around 15–30 working days from when the laboratory receives the sample.
Do I only need to take this test once?
Yes. Germline DNA does not usually change over time, so hereditary cancer risk testing is generally a one-time test.
Does a positive result mean I will get cancer?
No. A positive result means you may have an increased inherited risk, but it does not mean cancer is certain.
Does a negative result mean I will never get cancer?
No. A negative result does not remove all cancer risk. It only means no reportable mutation was found in the genes tested.
Which cancers can be assessed?
Panels are available for breast, ovarian, uterine, colon, gastric, pancreatic, prostate, melanoma, renal, cerebral tumours, thyroid-related risk and other hereditary cancer groups.
Is BRCA testing included?
BRCA1 and BRCA2 testing is available either as a focused BRCA panel or as part of wider hereditary cancer panels.
Should I speak to a healthcare professional before testing?
Yes. Genetic testing can have implications for you and your relatives, so pre- and post-test counselling or healthcare professional discussion is strongly recommended.
We offer a wide range of blood tests, but the list below is not comprehensive. If you can’t find what you need or need more information, please feel free to contact us at 01138301371 and speak to one of our healthcare professionals. We’ll be more than happy to help you out.
- We provide a same-day blood result service for some blood tests (Monday – Saturday, excluding Bank Holidays).
- A £ 25 fee for Phlebotomy + Courier charge will be applied for all Bloods. Please inform us at the time of booking if you require same-day results.
- The Appropriate cancellation charge will apply as shown below.
- Amendments: 72 hrs ( 3 days Notice )
- Bookings made on the same day or 1 to 3 days before your appointment cannot be amended.
- Refund Applicable: 14 Days or more: Full refund
- Between 10 and 14 days: £30 non-refundable deposit balance paid will be refunded
- Between 1 and 9 days: No refund will be given
- Failure to attend: No refund will be given
- Rescheduled Appointments are not eligible for Cancellation or Refunds.
At Miracle Inside Diagnostic Scan Centre, we firmly believe that knowledge is the cornerstone of good health. Our dedicated team is committed to supporting you on your unique health journey, offering expertise, compassion, and confidentiality every step of the way.
To Get Your appointment booked, please CLICK HERE